I develop web applications and have been testing chrome on the sites I manage. I notice that the JavaScript part runs notably faster than Firefox and Safari (chrome's closest relative), then goes for circles around IE6 and IE7. However I think safari will do the initial loading of the page faster, and chrome has an issue right now (I tested on external sites to verify it wasn't just our work) where it will periodically do incomplete loads (hitting refresh will completely load the page), but this will probably be one of the first issues addressed.
The main area that it has benefits is if the pages have heavy JavaScript/AJAX usage, especially if you are running many tabs and as the number of cores you have in your computer increases. Features I like is pulling tabs off and they become their own window (granted already on safari). Followed closely native support for pages to load once then practically be an application on the desktop.
The release of Firefox 3, Safari 4, IE8 and Chrome has me optimistic the coming year will be the best for cross platform development. If only IE8 after it's release could take the majority of IE's market share away from IE6 and IE7 quickly it would make my year. IE6 can burn in hell, hopefully IE7 will just have a quick quiet death. These would cut out 70% of the testing and debugging I do.
